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设计合成了一种新型耐尔蓝衍生物2-{9-(二甲基氨基)-10-甲基-9H-苯并[a]吩嗪-5-羰基}-N-苯基肼硫代酰胺盐酸盐(EPNH),其结构得到了1HNMR、ESI-MS和元素分析的确认。实验结果表明,该化合物在p H 7.4的HEPES缓冲液中,对Hg2+表现出高选择性和高灵敏度的荧光和显色传感;当Hg2+浓度在0.020.25μmol/L范围内时,线性相关系数R=0.997 7,最低检出限为0.01μmol/L(n=6)。
Abstract：A new nile blue derivative 2-( 9-( ethylimino)-10-methyl-9H-benzo[a]phenoxazine-5-carbonyl)-N-phenyl hydrazine carbothioamide hydrochloride( EPNH) was synthesized. The structure was confirmed by1 HNMR,ESI-MS and elemental analyses. The results show that EPNH exhibited a high selectivity for Hg2 +and high sensitivity fluorescence response. It exhibited a dynamic response concentration range for Hg2 +from 0. 02 to 0. 25 μmol / L with a detection limit of 0. 01 μmol / L( n = 6) and the linear correlation coefficient was 0. 997 7.
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基本信息:
DOI：10.13822/j.cnki.hxsj.2015.02.016
中图分类号:O626
引用信息:
[1]徐鉴.一种新型耐尔蓝衍生物的合成及其对Hg~(2+)识别研究[J].化学试剂,2015,37(02):158-160+164.DOI:10.13822/j.cnki.hxsj.2015.02.016.
基金信息:
南京晓庄学院校级科研资助项目(2013NXY37)
2015-02-15
2015-02-15